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Resistance of Klebsiella pneumoniae to Phage hvKpP3 Due to High-Molecular Weight Lipopolysaccharide Synthesis Failure

The spread of multidrug resistant and hypervirulent Klebsiella pneumoniae has recently increased. Phages have been considered alternatives for treating infections caused by tenacious pathogens. Our study describes a novel lytic Klebsiella phage, hvKpP3, and we obtained spontaneous mutants, hvKpP3R a...

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Detalles Bibliográficos
Autores principales: Geng, Huaixin, Song, Lingjie, Yang, Xianggui, Xing, Siyu, Wang, Rui, Xu, Ying, Jia, Xu, Luan, Guangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269817/
https://www.ncbi.nlm.nih.gov/pubmed/37022197
http://dx.doi.org/10.1128/spectrum.04384-22