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Heme Oxygenase-1 and Its Metabolites Carbon Monoxide and Biliverdin, but Not Iron, Exert Antiviral Activity against Porcine Circovirus Type 3

Porcine circovirus type 3 (PCV3) is a newly discovered pathogen that causes porcine dermatitis and nephropathy syndrome (PDNS)-like clinical signs, multisystemic inflammation, and reproductive failure. Heme oxygenase-1 (HO-1), a stress-inducible enzyme, exerts protective functions by converting heme...

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Detalles Bibliográficos
Autores principales: Hou, Lei, Yang, Xiaoyu, Liu, Changzhe, Guo, Jinshuo, Shi, Yongyan, Sun, Tong, Feng, Xufei, Zhou, Jianwei, Liu, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269822/
https://www.ncbi.nlm.nih.gov/pubmed/37140466
http://dx.doi.org/10.1128/spectrum.05060-22