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K(2)CO(3)-promoted synthesis of amides from 1-aryl-2,2,2-trifluoroethanones and amines under mild conditions

A base-promoted amidation of 1-aryl-2,2,2-trifluoroethanones with amines via Haller–Bauer reaction has been developed. In this reaction, the direct transformation of 1-aryl-2,2,2-trifluoroethanones into amides via C(O)–C bond cleavage occurs without the use of any stoichiometric chemical oxidants or...

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Detalles Bibliográficos
Autores principales: Zhong, Pinyong, Wang, Yu-Chao, Liu, Jin-Biao, Zhang, Linjun, Luo, Nianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269829/
https://www.ncbi.nlm.nih.gov/pubmed/37333725
http://dx.doi.org/10.1039/d3ra03329e