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Helicobacter pylori Modulates Heptose Metabolite Biosynthesis and Heptose-Dependent Innate Immune Host Cell Activation by Multiple Mechanisms

Heptose metabolites including ADP-d-glycero-β-d-manno-heptose (ADP-heptose) are involved in bacterial lipopolysaccharide and cell envelope biosynthesis. Recently, heptoses were also identified to have potent proinflammatory activity on human cells as novel microbe-associated molecular patterns. The...

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Detalles Bibliográficos
Autores principales: Hauke, Martina, Metz, Felix, Rapp, Johanna, Faass, Larissa, Bats, Simon H., Radziej, Sandra, Link, Hannes, Eisenreich, Wolfgang, Josenhans, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269868/
https://www.ncbi.nlm.nih.gov/pubmed/37129481
http://dx.doi.org/10.1128/spectrum.03132-22