CLEC18A Impairs Phagocytosis by Reducing FcγRIIA Expression and Arresting Autophagosome-Lysosome Fusion

Mixed cryoglobulinemia (MC) is a hepatitis C virus (HCV)–related extrahepatic manifestation that is characterized by the abnormal presence of immune complexes (ICs). This may be due to the reduced uptake and clearance of ICs. The C-type lectin member 18A (CLEC18A) is a secretory protein that is expr...

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Detalles Bibliográficos
Autores principales: Liao, Tsai-Ling, Chen, Yi-Ming, Tang, Kuo-Tung, Yang, Ying-Ying, Chen, Der-Yuan, Chan, Tsung-Hsien, Tsai, Hui-Ju, Hsieh, Shie-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269929/
https://www.ncbi.nlm.nih.gov/pubmed/37154715
http://dx.doi.org/10.1128/spectrum.02903-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269929/
https://www.ncbi.nlm.nih.gov/pubmed/37154715
http://dx.doi.org/10.1128/spectrum.02903-22

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