Germ cell-specific eIF4E1b regulates maternal mRNA translation to ensure zygotic genome activation

Translation of maternal mRNAs is detected before transcription of zygotic genes and is essential for mammalian embryo development. How certain maternal mRNAs are selected for translation instead of degradation and how this burst of translation affects zygotic genome activation remain unknown. Using...

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Detalles Bibliográficos
Autores principales: Yang, Guanghui, Xin, Qiliang, Feng, Iris, Wu, Di, Dean, Jurrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270193/
https://www.ncbi.nlm.nih.gov/pubmed/37257918
http://dx.doi.org/10.1101/gad.350400.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270193/
https://www.ncbi.nlm.nih.gov/pubmed/37257918
http://dx.doi.org/10.1101/gad.350400.123

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