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Analysis of the Drosophila and human DPR elements reveals a distinct human variant whose specificity can be enhanced by machine learning
The RNA polymerase II core promoter is the site of convergence of the signals that lead to the initiation of transcription. Here, we performed a comparative analysis of the downstream core promoter region (DPR) in Drosophila and humans by using machine learning. These studies revealed a distinct hum...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270198/ https://www.ncbi.nlm.nih.gov/pubmed/37163335 http://dx.doi.org/10.1101/gad.350572.123 |