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LRRK2 and Parkinson's disease: from genetics to targeted therapy
LRRK2 variants are implicated in both familial and sporadic PD. LRRK2‐PD has a generally benign clinical presentation and variable pathology, with inconsistent presence of Lewy bodies and marked Alzheimer's disease pathology. The mechanisms underlying LRRK2‐PD are still unclear, but inflammatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270275/ https://www.ncbi.nlm.nih.gov/pubmed/37021623 http://dx.doi.org/10.1002/acn3.51776 |