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The SERPINA5 coding variant E228Q does not contribute to clinicopathologic characteristics in Alzheimer’s disease: A cross-sectional study

We previously demonstrated that increased expression of the SERPINA5 gene is associated with hippocampal vulnerability in Alzheimer’s disease (AD) brains. SERPINA5 was further demonstrated to be a novel tau-binding partner that colocalizes within neurofibrillary tangles. Our goal was to determine wh...

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Detalles Bibliográficos
Autores principales: Matchett, Billie J., Lincoln, Sarah J., Baker, Matt, Tamvaka, Nikoleta, Labuzan, Sydney A., Hicks Sirmans, Tiffany N., Moloney, Christina M., Helminger, Jacqueline, Hinkle, Kelly M., Cabrera-Rodriguez, Janisse, Wickland, Daniel P., Johnson, Patrick W., Heckman, Michael G., Reddy, Joseph S., Younkin, Steven G., Carrasquillo, Minerva M., Duara, Ranjan, Graff-Radford, Neill R., Pottier, Cyril, Ertekin-Taner, Nilüfer, Ross, Owen A., Rademakers, Rosa, Dickson, Dennis W., Murray, Melissa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270469/
https://www.ncbi.nlm.nih.gov/pubmed/37327267
http://dx.doi.org/10.1097/MD.0000000000034017