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Variants of CARD8 in Leishmania guyanensis-cutaneous leishmaniasis and influence of the variants genotypes on circulating plasma cytokines IL-1β, TNFα and IL-8

Nucleotide-binding oligomerization domain, leucine-rich repeat-containing protein family (NLR) are intracellular pathogen recognition receptors mediating innate immunity, releasing proinflammatory cytokines IL-1β and IL-18, and promoting pyroptotic cell death, upon sensing pathogenic or endogenous d...

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Detalles Bibliográficos
Autores principales: Sequera, Héctor David Graterol, de Souza, Josué Lacerda, Junior, José do Espírito Santo, da Silva, Lener Santos, Pinheiro, Suzana Kanawati, Kerr, Herllon Karllos Athaydes, de Souza, Mara Lúcia Gomes, Guerra, Marcus Vinitius de Farias, de Mesquita, Tirza Gabrielle Ramos, Ramasawmy, Rajendranath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270566/
https://www.ncbi.nlm.nih.gov/pubmed/37276232
http://dx.doi.org/10.1371/journal.pntd.0011416