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A holistic view of muscle metabolic reprogramming through personalized metabolic modeling in newly diagnosed diabetic patients

Type 2 diabetes mellitus (T2DM) is a challenging and progressive metabolic disease caused by insulin resistance. Skeletal muscle is the major insulin-sensitive tissue that plays a pivotal role in blood sugar homeostasis. Dysfunction of muscle metabolism is implicated in the disturbance of glucose ho...

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Detalles Bibliográficos
Autores principales: Khoshnejat, Maryam, Banaei-Moghaddam, Ali Mohammad, Moosavi-Movahedi, Ali Akbar, Kavousi, Kaveh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270629/
https://www.ncbi.nlm.nih.gov/pubmed/37319295
http://dx.doi.org/10.1371/journal.pone.0287325