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Quality comparison of a state-of-the-art preparation of a recombinant L-asparaginase derived from Escherichia coli with an alternative asparaginase product

L-asparaginase (ASNase) is a protein that is essential for the treatment of acute lymphoblastic leukemia (ALL). The main types of ASNase that are clinically used involve native and pegylated Escherichia coli (E. coli)-derived ASNase as well as Erwinia chrysanthemi-derived ASNase. Additionally, a new...

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Detalles Bibliográficos
Autores principales: Schnuchel, Arndt, Radcke, Christoph, Theobald, Lars, Doeding, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270636/
https://www.ncbi.nlm.nih.gov/pubmed/37319282
http://dx.doi.org/10.1371/journal.pone.0285948