Cargando…

Cingulate circuits are associated with escalation of heroin use and naloxone-induced increases in heroin self-administration

Opioid use disorder (OUD) is defined as a compulsion to seek and take opioids, loss of control over intake and the development of a negative emotional state when access to opioids is denied. Using functional magnetic resonance imaging (fMRI) data in a rat model of OUD, we demonstrate that the escala...

Descripción completa

Detalles Bibliográficos
Autores principales: Scarlata, MJ, Keeley, RJ, Carmack, SA, Tsai, P-J, Vendruscolo, JCM, Lu, H, Koob, GF, Vendruscolo, LF, Stein, EA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270679/
https://www.ncbi.nlm.nih.gov/pubmed/37323812
http://dx.doi.org/10.1016/j.addicn.2021.100002