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Cingulate circuits are associated with escalation of heroin use and naloxone-induced increases in heroin self-administration
Opioid use disorder (OUD) is defined as a compulsion to seek and take opioids, loss of control over intake and the development of a negative emotional state when access to opioids is denied. Using functional magnetic resonance imaging (fMRI) data in a rat model of OUD, we demonstrate that the escala...
Autores principales: | Scarlata, MJ, Keeley, RJ, Carmack, SA, Tsai, P-J, Vendruscolo, JCM, Lu, H, Koob, GF, Vendruscolo, LF, Stein, EA |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270679/ https://www.ncbi.nlm.nih.gov/pubmed/37323812 http://dx.doi.org/10.1016/j.addicn.2021.100002 |
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