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Bacterial meningitis in the early postnatal mouse studied at single-cell resolution

Bacterial meningitis is a major cause of morbidity and mortality, especially among infants and the elderly. Here, we study mice to assess the response of each of the major meningeal cell types to early postnatal E. coli infection using single nucleus RNA sequencing (snRNAseq), immunostaining, and ge...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Rattner, Amir, Nathans, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270687/
https://www.ncbi.nlm.nih.gov/pubmed/37318981
http://dx.doi.org/10.7554/eLife.86130