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Developing a 3-D computational model of neurons in the central amygdala to understand pharmacological targets for pain

Neuropathic and nociplastic pain are major causes of pain and involve brain areas such as the central nucleus of the amygdala (CeA). Within the CeA, neurons expressing protein kinase c-delta (PKCδ) or somatostatin (SST) have opposing roles in pain-like modulation. In this manuscript, we describe our...

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Detalles Bibliográficos
Autores principales: Miller Neilan, Rachael, Reith, Carley, Anandan, Iniya, Kraeuter, Kayla, Allen, Heather N., Kolber, Benedict J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10270735/
https://www.ncbi.nlm.nih.gov/pubmed/37332477
http://dx.doi.org/10.3389/fpain.2023.1183553