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Diazoxide Choline Extended-Release Tablet in People With Prader-Willi Syndrome: A Double-Blind, Placebo-Controlled Trial

CONTEXT: Prader-Willi syndrome (PWS) is a rare neurobehavioral-metabolic disease caused by the lack of paternally expressed genes in the chromosome 15q11-q13 region, characterized by hypotonia, neurocognitive problems, behavioral difficulties, endocrinopathies, and hyperphagia resulting in severe ob...

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Detalles Bibliográficos
Autores principales: Miller, Jennifer L, Gevers, Evelien, Bridges, Nicola, Yanovski, Jack A, Salehi, Parisa, Obrynba, Kathryn S, Felner, Eric I, Bird, Lynne M, Shoemaker, Ashley H, Angulo, Moris, Butler, Merlin G, Stevenson, David, Abuzzahab, Jennifer, Barrett, Timothy, Lah, Melissa, Littlejohn, Elizabeth, Mathew, Verghese, Cowen, Neil M, Bhatnagar, Anish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10271219/
https://www.ncbi.nlm.nih.gov/pubmed/36639249
http://dx.doi.org/10.1210/clinem/dgad014