SEC-seq: association of molecular signatures with antibody secretion in thousands of single human plasma cells

The secreted products of cells drive many functions in vivo; however, methods to link this functional information to surface markers and transcriptomes have been lacking. By accumulating secretions close to secreting cells held within cavity-containing hydrogel nanovials, we demonstrate workflows to...

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Detalles Bibliográficos
Autores principales: Cheng, Rene Yu-Hong, de Rutte, Joseph, Ito, Cade Ellis K., Ott, Andee R., Bosler, Lucie, Kuo, Wei-Ying, Liang, Jesse, Hall, Brian E., Rawlings, David J., Di Carlo, Dino, James, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272111/
https://www.ncbi.nlm.nih.gov/pubmed/37322036
http://dx.doi.org/10.1038/s41467-023-39367-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272111/
https://www.ncbi.nlm.nih.gov/pubmed/37322036
http://dx.doi.org/10.1038/s41467-023-39367-8

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