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SEC-seq: association of molecular signatures with antibody secretion in thousands of single human plasma cells
The secreted products of cells drive many functions in vivo; however, methods to link this functional information to surface markers and transcriptomes have been lacking. By accumulating secretions close to secreting cells held within cavity-containing hydrogel nanovials, we demonstrate workflows to...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272111/ https://www.ncbi.nlm.nih.gov/pubmed/37322036 http://dx.doi.org/10.1038/s41467-023-39367-8 |