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Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy

Amyloid proteins are associated with a broad spectrum of neurodegenerative diseases. However, it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment. To address this challenge, we developed a computational chem...

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Detalles Bibliográficos
Autores principales: Zhao, Jian, Jiang, Lulu, Matlock, Alex, Xu, Yihong, Zhu, Jiabei, Zhu, Hongbo, Tian, Lei, Wolozin, Benjamin, Cheng, Ji-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272128/
https://www.ncbi.nlm.nih.gov/pubmed/37322011
http://dx.doi.org/10.1038/s41377-023-01191-6