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Molecular mechanisms of Holliday junction branch migration catalyzed by an asymmetric RuvB hexamer
The Holliday junction (HJ) is a DNA intermediate of homologous recombination, involved in many fundamental physiological processes. RuvB, an ATPase motor protein, drives branch migration of the Holliday junction with a mechanism that had yet to be elucidated. Here we report two cryo-EM structures of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272136/ https://www.ncbi.nlm.nih.gov/pubmed/37322069 http://dx.doi.org/10.1038/s41467-023-39250-6 |