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Molecular mechanisms of Holliday junction branch migration catalyzed by an asymmetric RuvB hexamer

The Holliday junction (HJ) is a DNA intermediate of homologous recombination, involved in many fundamental physiological processes. RuvB, an ATPase motor protein, drives branch migration of the Holliday junction with a mechanism that had yet to be elucidated. Here we report two cryo-EM structures of...

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Detalles Bibliográficos
Autores principales:	Rish, Anthony D., Shen, Zhangfei, Chen, Zhenhang, Zhang, Nan, Zheng, Qingfei, Fu, Tian-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272136/ https://www.ncbi.nlm.nih.gov/pubmed/37322069 http://dx.doi.org/10.1038/s41467-023-39250-6

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