Cargando…

Peroxisome proliferator-activated receptor-α activation facilitates contextual fear extinction and modulates intrinsic excitability of dentate gyrus neurons

The dentate gyrus (DG) of the hippocampus encodes contextual information associated with fear, and cell activity in the DG is required for acquisition and extinction of contextual fear. However, the underlying molecular mechanisms are not fully understood. Here we show that mice deficient for peroxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiang, Guo, Liu, Xia, Wang, Jiangong, Lu, Shunshun, Yu, Meng, Zhang, Yuhan, Sun, Bin, Huang, Bin, Lu, Xin-Yun, Li, Xingang, Zhang, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272150/
https://www.ncbi.nlm.nih.gov/pubmed/37322045
http://dx.doi.org/10.1038/s41398-023-02496-1