Cargando…
Peroxisome proliferator-activated receptor-α activation facilitates contextual fear extinction and modulates intrinsic excitability of dentate gyrus neurons
The dentate gyrus (DG) of the hippocampus encodes contextual information associated with fear, and cell activity in the DG is required for acquisition and extinction of contextual fear. However, the underlying molecular mechanisms are not fully understood. Here we show that mice deficient for peroxi...
Autores principales: | Xiang, Guo, Liu, Xia, Wang, Jiangong, Lu, Shunshun, Yu, Meng, Zhang, Yuhan, Sun, Bin, Huang, Bin, Lu, Xin-Yun, Li, Xingang, Zhang, Di |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272150/ https://www.ncbi.nlm.nih.gov/pubmed/37322045 http://dx.doi.org/10.1038/s41398-023-02496-1 |
Ejemplares similares
-
Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors
por: Zhang, D, et al.
Publicado: (2017) -
Elevated activity in the dorsal dentate gyrus reduces expression of fear memory after fear extinction training
por: Zhang, Yujie, et al.
Publicado: (2021) -
Plasticity of intrinsic excitability in mature granule cells of the dentate gyrus
por: Lopez-Rojas, Jeffrey, et al.
Publicado: (2016) -
Sexually dimorphic muscarinic acetylcholine receptor modulation of contextual fear learning in the dentate gyrus
por: Yavas, Ersin, et al.
Publicado: (2021) -
Loss of Ensemble Segregation in Dentate Gyrus, but not in Somatosensory Cortex, during Contextual Fear Memory Generalization
por: Yokoyama, Marie, et al.
Publicado: (2016)