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Patient-derived zebrafish xenografts of uveal melanoma reveal ferroptosis as a drug target

Uveal melanoma (UM) has a high risk to progress to metastatic disease with a median survival of 3.9 months after metastases detection, as metastatic UM responds poorly to conventional and targeted chemotherapy and is largely refractory to immunotherapy. Here, we present a patient-derived zebrafish U...

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Detalles Bibliográficos
Autores principales: Groenewoud, Arwin, Yin, Jie, Gelmi, Maria Chiara, Alsafadi, Samar, Nemati, Fariba, Decaudin, Didier, Roman-Roman, Sergio, Kalirai, Helen, Coupland, Sarah E., Jochemsen, Aart G., Jager, Martine J., Engel, Felix B., Snaar-Jagalska, B. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272172/
https://www.ncbi.nlm.nih.gov/pubmed/37321991
http://dx.doi.org/10.1038/s41420-023-01446-6