Ancient medicinal plant rosemary contains a highly efficacious and isoform-selective KCNQ potassium channel opener

Voltage-gated potassium (Kv) channels in the KCNQ subfamily serve essential roles in the nervous system, heart, muscle and epithelia. Different heteromeric KCNQ complexes likely serve distinct functions in the brain but heteromer subtype-specific small molecules for research or therapy are lacking....

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Detalles Bibliográficos
Autores principales: Manville, Rían W., Hogenkamp, Derk, Abbott, Geoffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272180/
https://www.ncbi.nlm.nih.gov/pubmed/37322081
http://dx.doi.org/10.1038/s42003-023-05021-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272180/
https://www.ncbi.nlm.nih.gov/pubmed/37322081
http://dx.doi.org/10.1038/s42003-023-05021-8

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