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Ancient medicinal plant rosemary contains a highly efficacious and isoform-selective KCNQ potassium channel opener
Voltage-gated potassium (Kv) channels in the KCNQ subfamily serve essential roles in the nervous system, heart, muscle and epithelia. Different heteromeric KCNQ complexes likely serve distinct functions in the brain but heteromer subtype-specific small molecules for research or therapy are lacking....
Autores principales: | Manville, Rían W., Hogenkamp, Derk, Abbott, Geoffrey W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272180/ https://www.ncbi.nlm.nih.gov/pubmed/37322081 http://dx.doi.org/10.1038/s42003-023-05021-8 |
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