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Biomedical knowledge graph learning for drug repurposing by extending guilt-by-association to multiple layers

Computational drug repurposing aims to identify new indications for existing drugs by utilizing high-throughput data, often in the form of biomedical knowledge graphs. However, learning on biomedical knowledge graphs can be challenging due to the dominance of genes and a small number of drug and dis...

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Detalles Bibliográficos
Autores principales: Bang, Dongmin, Lim, Sangsoo, Lee, Sangseon, Kim, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272215/
https://www.ncbi.nlm.nih.gov/pubmed/37322032
http://dx.doi.org/10.1038/s41467-023-39301-y