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Leveraging mathematical modeling to analyze nonadherence for hydroxyurea therapy in sickle cell disease

Nonadherence is common in individuals with sickle cell disease (SCD) on hydroxyurea therapy and can be observed with waning improvements in hematologic parameters or biomarkers like mean cell volume and fetal hemoglobin level over time. We modeled the impact of hydroxyurea nonadherence on longitudin...

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Detalles Bibliográficos
Autores principales: Pandey, Akancha, Raja, Rubesh, Estepp, Jeremie H., Ramkrishna, Doraiswami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272301/
https://www.ncbi.nlm.nih.gov/pubmed/37194405
http://dx.doi.org/10.1002/psp4.12945