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Leveraging mathematical modeling to analyze nonadherence for hydroxyurea therapy in sickle cell disease
Nonadherence is common in individuals with sickle cell disease (SCD) on hydroxyurea therapy and can be observed with waning improvements in hematologic parameters or biomarkers like mean cell volume and fetal hemoglobin level over time. We modeled the impact of hydroxyurea nonadherence on longitudin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272301/ https://www.ncbi.nlm.nih.gov/pubmed/37194405 http://dx.doi.org/10.1002/psp4.12945 |