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Genetic and non‐genetic factors influencing efavirenz population pharmacokinetics among human immunodeficiency virus‐1‐infected children in Ethiopia

Despite the potential for efavirenz (EFV) to be an effective alternative antiretroviral agent, its sources of wide inter‐ and intra‐individual pharmacokinetic (PK) variability are not well‐characterized in children. We investigated the effects of genetic and non‐genetic factors, including demographi...

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Detalles Bibliográficos
Autores principales: Chala, Adugna, Kitabi, Eliford Ngaimisi, Ahmed, Jemal Hussien, Tadesse, Birkneh Tilahun, Chaka, Tolossa Eticha, Makonnen, Eyasu, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272302/
https://www.ncbi.nlm.nih.gov/pubmed/36840416
http://dx.doi.org/10.1002/psp4.12951