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Genetic and non‐genetic factors influencing efavirenz population pharmacokinetics among human immunodeficiency virus‐1‐infected children in Ethiopia
Despite the potential for efavirenz (EFV) to be an effective alternative antiretroviral agent, its sources of wide inter‐ and intra‐individual pharmacokinetic (PK) variability are not well‐characterized in children. We investigated the effects of genetic and non‐genetic factors, including demographi...
Autores principales: | Chala, Adugna, Kitabi, Eliford Ngaimisi, Ahmed, Jemal Hussien, Tadesse, Birkneh Tilahun, Chaka, Tolossa Eticha, Makonnen, Eyasu, Aklillu, Eleni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272302/ https://www.ncbi.nlm.nih.gov/pubmed/36840416 http://dx.doi.org/10.1002/psp4.12951 |
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