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A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes

Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by abnormally high blood glucose concentrations due to dysfunction of the insulin‐producing beta‐cells in the pancreas. Dapagliflozin, an inhibitor of renal glucose reabsorption, has the potential to improve often suboptimal glyc...

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Detalles Bibliográficos
Autores principales: Sokolov, Victor, Yakovleva, Tatiana, Stolbov, Leonid, Penland, Robert C., Boulton, David, Parkinson, Joanna, Tang, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272306/
https://www.ncbi.nlm.nih.gov/pubmed/36912425
http://dx.doi.org/10.1002/psp4.12956