PK/PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris

In vitro combination of echinocandins and isavuconazole against the emerging species Candida auris is mainly synergistic. However, this combination has not been evaluated in clinical settings. A pharmacokinetic/pharmacodynamic modeling and simulation approach based on in vitro data may be helpful to...

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Detalles Bibliográficos
Autores principales: Caballero, Unai, Eraso, Elena, Quindós, Guillermo, Vozmediano, Valvanera, Schmidt, Stephan, Jauregizar, Nerea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272309/
https://www.ncbi.nlm.nih.gov/pubmed/36915233
http://dx.doi.org/10.1002/psp4.12949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272309/
https://www.ncbi.nlm.nih.gov/pubmed/36915233
http://dx.doi.org/10.1002/psp4.12949

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