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Identification of autoantigens and their potential post-translational modification in EGPA and severe eosinophilic asthma

BACKGROUND: The chronic airway inflammation in severe eosinophilic asthma (SEA) suggests potential autoimmune aetiology with unidentified autoantibodies analogous to myeloperoxidase (MPO) in ANCA-positive EGPA (eosinophilic granulomatosis with polyangiitis). Previous research has shown that oxidativ...

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Detalles Bibliográficos
Autores principales: Esposito, Ilaria, Kontra, Ioanna, Giacomassi, Chiara, Manou-Stathopoulou, Sotiria, Brown, James, Stratton, Richard, Verykokou, Galateia, Buccafusca, Roberto, Stevens, Michael, Nissim, Ahuva, Lewis, Myles J., Pfeffer, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272393/
https://www.ncbi.nlm.nih.gov/pubmed/37334358
http://dx.doi.org/10.3389/fimmu.2023.1164941