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The roles of XJ13 and XJ44-specific mutations within the Candid #1 GPC in Junin virus attenuation

Junin virus (JUNV) is a member of the Arenaviridae family of viruses and is the pathogen responsible for causing Argentine hemorrhagic fever, a potentially lethal disease endemic to Argentina. A live attenuated vaccine for human use, called Candid#1, is approved only in Argentina. Candid#1 vaccine s...

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Detalles Bibliográficos
Autores principales: Manning, John Tyler, Maruyama, Junki, Wanninger, Timothy, Reyna, Rachel A., Stevenson, Heather L., Peng, Bi-Hung, Mantlo, Emily K., Huang, Cheng, Paessler, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272451/
https://www.ncbi.nlm.nih.gov/pubmed/37334351
http://dx.doi.org/10.3389/fimmu.2023.1172792