Differential response of C9orf72 transcripts following neuronal depolarization

The (G(4)C(2))(n) nucleotide repeat expansion (NRE) mutation in C9orf72 is the most common genetic cause of ALS and FTD. The biological functions of C9orf72 are becoming understood, but it is unclear if this gene is regulated in a neural-specific manner. Neuronal activity is a crucial modifier of bi...

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Detalles Bibliográficos
Autores principales: Ghaffari, Layla T., Trotti, Davide, Haeusler, Aaron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272498/
https://www.ncbi.nlm.nih.gov/pubmed/37332610
http://dx.doi.org/10.1016/j.isci.2023.106959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272498/
https://www.ncbi.nlm.nih.gov/pubmed/37332610
http://dx.doi.org/10.1016/j.isci.2023.106959

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