SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury

Recent evidences have implicated that SENP3 is a deSUMOylase which possesses neuronal damage effects in cerebral ischemia. However, its role in microglia remains poorly understood. Here, we found that SENP3 was upregulated in the peri-infarct areas of mice following ischemic stroke. Furthermore, kno...

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Detalles Bibliográficos
Autores principales: Xia, Qian, Mao, Meng, Zhan, Gaofeng, Luo, Zhenzhao, Zhao, Yin, Li, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272502/
https://www.ncbi.nlm.nih.gov/pubmed/37332598
http://dx.doi.org/10.1016/j.isci.2023.106953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272502/
https://www.ncbi.nlm.nih.gov/pubmed/37332598
http://dx.doi.org/10.1016/j.isci.2023.106953

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