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SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
Recent evidences have implicated that SENP3 is a deSUMOylase which possesses neuronal damage effects in cerebral ischemia. However, its role in microglia remains poorly understood. Here, we found that SENP3 was upregulated in the peri-infarct areas of mice following ischemic stroke. Furthermore, kno...
Autores principales: | Xia, Qian, Mao, Meng, Zhan, Gaofeng, Luo, Zhenzhao, Zhao, Yin, Li, Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272502/ https://www.ncbi.nlm.nih.gov/pubmed/37332598 http://dx.doi.org/10.1016/j.isci.2023.106953 |
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