Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis

Glaucoma is a serious complication of glucocorticoid (GC) therapy arising through elevations in intraocular pressure (IOP). Dexamethasone (DEX) is reported to contribute to elevated IOP through different effects on the trabecular meshwork but whether DEX contributes to glaucoma development through t...

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Detalles Bibliográficos
Autores principales: Li, Haijun, Ren, Jing, Cui, Huiling, Wang, Di, Zhao, Rumeng, Liu, Xiaohui, Tian, Shuai, Wang, Jing, Zhang, Jingyi, Li, Peng, Thorne, Rick F., Duan, Shichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272683/
https://www.ncbi.nlm.nih.gov/pubmed/37265069
http://dx.doi.org/10.1177/09636897231177356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272683/
https://www.ncbi.nlm.nih.gov/pubmed/37265069
http://dx.doi.org/10.1177/09636897231177356

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