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IL-27-containing exosomes secreted by innate B-1a cells suppress and ameliorate uveitis
INTRODUCTION: IL-27 is a heterodimeric cytokine composed of Ebi3 and IL-27p28 and can exert proinflammatory or immune suppressive effects depending on the physiological context. Ebi3 does not contain membrane-anchoring motifs, suggesting that it is a secreted protein while IL-27p28 is poorly secrete...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272713/ https://www.ncbi.nlm.nih.gov/pubmed/37334383 http://dx.doi.org/10.3389/fimmu.2023.1071162 |