Hypoxia-inducible factor activation promotes osteogenic transition of valve interstitial cells and accelerates aortic valve calcification in a mice model of chronic kidney disease

INTRODUCTION: Valve calcification (VC) is a widespread complication in chronic kidney disease (CKD) patients. VC is an active process with the involvement of in situ osteogenic transition of valve interstitial cells (VICs). VC is accompanied by the activation of hypoxia inducible factor (HIF) pathwa...

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Detalles Bibliográficos
Autores principales: Csiki, Dávid Máté, Ababneh, Haneen, Tóth, Andrea, Lente, Gréta, Szöőr, Árpád, Tóth, Anna, Fillér, Csaba, Juhász, Tamás, Nagy, Béla, Balogh, Enikő, Jeney, Viktória
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272757/
https://www.ncbi.nlm.nih.gov/pubmed/37332579
http://dx.doi.org/10.3389/fcvm.2023.1168339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272757/
https://www.ncbi.nlm.nih.gov/pubmed/37332579
http://dx.doi.org/10.3389/fcvm.2023.1168339

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