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Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria
Mitochondrial dysfunction and cellular senescence are hallmarks of aging. However, the relationship between these two phenomena remains incompletely understood. In this study, we investigated the rewiring of mitochondria upon development of the senescent state in human IMR90 fibroblasts. Determining...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272782/ https://www.ncbi.nlm.nih.gov/pubmed/37321846 http://dx.doi.org/10.26508/lsa.202302127 |