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Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria

Mitochondrial dysfunction and cellular senescence are hallmarks of aging. However, the relationship between these two phenomena remains incompletely understood. In this study, we investigated the rewiring of mitochondria upon development of the senescent state in human IMR90 fibroblasts. Determining...

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Detalles Bibliográficos
Autores principales: Kim, Jun Yong, Atanassov, Ilian, Dethloff, Frederik, Kroczek, Lara, Langer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272782/
https://www.ncbi.nlm.nih.gov/pubmed/37321846
http://dx.doi.org/10.26508/lsa.202302127