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Targeting CD137 (4-1BB) towards improved safety and efficacy for cancer immunotherapy

T cells play a critical role in antitumor immunity, where T cell activation is regulated by both inhibitory and costimulatory receptor signaling that fine-tune T cell activity during different stages of T cell immune responses. Currently, cancer immunotherapy by targeting inhibitory receptors such a...

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Detalles Bibliográficos
Autores principales: Liu, Guizhong, Luo, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272836/
https://www.ncbi.nlm.nih.gov/pubmed/37334375
http://dx.doi.org/10.3389/fimmu.2023.1208788