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Low avidity circulating SARS-CoV-2 reactive CD8+ T cells with proinflammatory TEMRA phenotype are associated with post-acute sequelae of COVID-19

The role of adaptive SARS-CoV-2 specific immunity in post-acute sequelae of COVID-19 (PASC) is not well explored, although a growing population of convalescent COVID-19 patients with manifestation of PASC is observed. We analyzed the SARS-CoV-2-specific immune response, via pseudovirus neutralizing...

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Detalles Bibliográficos
Autores principales: Paniskaki, Krystallenia, Konik, Margarethe J., Anft, Moritz, Heidecke, Harald, Meister, Toni L., Pfaender, Stephanie, Krawczyk, Adalbert, Zettler, Markus, Jäger, Jasmin, Gaeckler, Anja, Dolff, Sebastian, Westhoff, Timm H., Rohn, Hana, Stervbo, Ulrik, Scheibenbogen, Carmen, Witzke, Oliver, Babel, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272838/
https://www.ncbi.nlm.nih.gov/pubmed/37333646
http://dx.doi.org/10.3389/fmicb.2023.1196721