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A lung-specific mutational signature enables inference of viral and bacterial respiratory niche

Exposure to different mutagens leaves distinct mutational patterns that can allow inference of pathogen replication niches. We therefore investigated whether SARS-CoV-2 mutational spectra might show lineage-specific differences, dependent on the dominant site(s) of replication and onwards transmissi...

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Detalles Bibliográficos
Autores principales: Ruis, Christopher, Peacock, Thomas P., Polo, Luis M., Masone, Diego, Alvarez, Maria Soledad, Hinrichs, Angie S., Turakhia, Yatish, Cheng, Ye, McBroome, Jakob, Corbett-Detig, Russell, Parkhill, Julian, Floto, R. Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272861/
https://www.ncbi.nlm.nih.gov/pubmed/37185044
http://dx.doi.org/10.1099/mgen.0.001018