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Whole-genome sequencing and transcriptome-characterized in vitro evolution of aminoglycoside resistance in Mycobacterium tuberculosis

Antibiotic resistance of Mycobacterium tuberculosis (Mtb) is a major public health concern worldwide. Therefore, it is of great significance to characterize the mutational pathways by which susceptible Mtb evolves into drug resistance. In this study, we used laboratory evolution to explore the mutat...

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Detalles Bibliográficos
Autores principales: Wei, Wenjing, Zhao, Yuchuan, Zhang, Chenchen, Yu, Meiling, Wu, Zhuhua, Xu, Liuyue, Peng, Kehao, Wu, Zhilong, Li, Yanxia, Wang, Xuezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272870/
https://www.ncbi.nlm.nih.gov/pubmed/37224060
http://dx.doi.org/10.1099/mgen.0.001022