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Diacerein modulates TLR4/ NF‐κB/IL‐1β and TRPC1/CHOP signalling pathways in gentamicin‐induced parotid toxicity in rats

The present study aimed to identify the possible protective effect of diacerein (DIA) on gentamicin (GNT)‐induced parotid toxicity in rats. DIA was administered in the presence and absence of GNT. Thirty‐two Wistar adult male rats were randomly arranged into four groups: control, DIA (50 mg/kg/day),...

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Detalles Bibliográficos
Autores principales: Ali, Dalia Mohamed, Mahmoud, Mohamed H., Rifaai, Rehab Ahmed, Fawzy, Michael Atef, Atta, Medhat, Welson, Nermeen N., Batiha, Gaber El‐Saber, Alexiou, Athanasios, Papadakis, Marios, Abdelzaher, Walaa Yehia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273056/
https://www.ncbi.nlm.nih.gov/pubmed/37257043
http://dx.doi.org/10.1111/jcmm.17791