Lyn‐mediated glycolysis enhancement of microglia contributes to neuropathic pain through facilitating IRF5 nuclear translocation in spinal dorsal horn

The pro‐inflammatory phenotype of microglia usually induces neuroinflammatory reactions in neuropathic pain. Glycometabolism shift to glycolysis can promote the pro‐inflammatory phenotype transition of microglia. The omics data analysis suggest a critical role for Lyn dysregulation in neuropathic pa...

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Detalles Bibliográficos
Autores principales: Kong, Erliang, Li, Yongchang, Ma, Peng, Zhang, Yixuan, Ding, Ruifeng, Hua, Tong, Yang, Mei, Yuan, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273059/
https://www.ncbi.nlm.nih.gov/pubmed/37132040
http://dx.doi.org/10.1111/jcmm.17759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273059/
https://www.ncbi.nlm.nih.gov/pubmed/37132040
http://dx.doi.org/10.1111/jcmm.17759

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