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Single-cell multi-omics analysis reveals dysfunctional Wnt signaling of spermatogonia in non-obstructive azoospermia

BACKGROUND: Non-obstructive azoospermia (NOA) is the most severe type that leads to 1% of male infertility. Wnt signaling governs normal sperm maturation. However, the role of Wnt signaling in spermatogonia in NOA has incompletely been uncovered, and upstream molecules regulating Wnt signaling remai...

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Detalles Bibliográficos
Autores principales: Zeng, Shengjie, Chen, Liuxun, Liu, Xvdong, Tang, Haibin, Wu, Hao, Liu, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273265/
https://www.ncbi.nlm.nih.gov/pubmed/37334314
http://dx.doi.org/10.3389/fendo.2023.1138386