Ion Mobility Mass Spectrometry Unveils Global Protein Conformations in Response to Conditions that Promote and Reverse Liquid–Liquid Phase Separation

[Image: see text] Liquid–liquid phase separation (LLPS) is a process by which biomacromolecules, particularly proteins, condense into a dense phase that resembles liquid droplets. Dysregulation of LLPS is implicated in disease, yet the relationship between protein conformational changes and LLPS rem...

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Detalles Bibliográficos
Autores principales: Robb, Christina Glen, Dao, Thuy P., Ujma, Jakub, Castañeda, Carlos A., Beveridge, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273310/
https://www.ncbi.nlm.nih.gov/pubmed/37276246
http://dx.doi.org/10.1021/jacs.3c00756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273310/
https://www.ncbi.nlm.nih.gov/pubmed/37276246
http://dx.doi.org/10.1021/jacs.3c00756

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